A brief summary of TNI's 14 human clinical trials
Tahitian Noni® Bioactive Beverages™ are more than simple fruit juices. There is real science behind the noni fruit, and no one is more dedicated to the study and research of noni than Tahitian Noni International.
Below are brief summaries of Tahitian Noni International’s 14 human clinical studies. These are peer-reviewed studies that have been published in major medical and food science journals. There is powerful information here; we encourage you to bookmark this article and share it with others.
1. Safety clinical trial
Conducted by: The British Industrial Biological Research Association (BIBRA).
Published in: Journal of Food Science
Description: 96 people, double-blind, placebo-controlled, one month trial, high dose of 750 ml/day (¾ bottle)
Results: TNJ absolutely safe & reduced number of illness related events
Link:http://www3.interscience.wiley.com/journal/118601402/abstract?CRETRY=1&SRETRY=0
2. Antioxidant activity in heavy smokers
Conducted by: The University of Illinois College of Medicine and TNI R&D
Published in: Chemistry Central Journal
Description: 285 people, double-blind, placebo-controlled, one month trial
Results: As little as 1 serving TNJ per day (30 mL or 1 oz) lowered free radicals significantly (fruit juice placebo had no significant effect)
Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765950/?tool=pubmed
3. DNA protection- aromatic DNA adducts in heavy smokers
Conducted by: The University of Illinois College of Medicine
Published in: The Journal, Nutrition and Cancer
Description: 203 people, double-blind, placebo-controlled, one month trial
Results: As little as 1 serving TNJ per day (30 mL or 1 oz) lowered amount of DNA damage by approximately half
Link:http://www.ncbi.nlm.nih.gov/pubmed/19838937?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2
4. Cholesterol & triglyceride lowering- in heavy smokers
Conducted by: The University of Illinois College of Medicine
Published in: Brief report published in the AHA journal, Circulation
Description: 132 people , double-blind, placebo-controlled, one month trial
Results: Cholesterol lowered by as much as 22%, triglycerides by as much as 54%, HDL increased by as much as 16%. Placebo had no effect
Link: http://circ.ahajournals.org/cgi/reprint/113/8/e301
5. Joint health of the neck (cervical spondylosis)
Conducted by: The University of Lagos College of Medicine
Published in: Nigerian Journal of Health and Biomedical Sciences
Description: 90 people, therapeutic control groups, one month trial
Results: 1 serving of TNJ alone improved range of movement & pain; combination of TNJ & standard therapy had further increased benefits
Link: http://www.ajol.info/viewarticle.php?id=29710
6. Energy/Endurance
Conducted by: The Moscow Scientific and Practical Center of Sports Medicine
Published in: Journal of Medicinal Plants Research
Description: 40 people, placebo-controlled, three week trial
Results: TNJ increased endurance by 21% and increased antioxidant activity by 25%. Placebo (blackberry juice) had no effect
Link: http://www.academicjournals.org/jmpr/PDF/pdf2008/July/Palu%20et%20al.pdf
7. Immune boosting & antioxidant
Conducted by: Tianjin Medical University
Published in: The Journal, Chinese Medical Research & Clinical
Description: 12 people , two month pilot study
Results: TNJ increased adaptive immune system activity by 32% and innate immune system activity by 30%. TNJ decreased oxidative stress in the body by 19%.
Link: http://www.cqvip.com/onlineread/onlineread.asp?ID=27818385
8. Drug screen test
Conducted by: TNI R&D
Published in: Journal of Medicinal Plants Research, in same paper as endurance trial
Description: 6 people, pilot study with urine drug screening tests
Results: TNJ does not contain illegal drugs or cause false positive results
Link: http://www.academicjournals.org/jmpr/PDF/pdf2008/July/Palu%20et%20al.pdf
9. Hypertension trial
Conducted by: Brigham Young University Hawaii
Published in: American Chemical Society Symposia Series No. 993, Functional Food and Health
Description: 10 people, one month open label trial
Results: 4 oz. TNJ per day significantly decreased blood pressure, especially systolic blood pressure
Link: http://pubs.acs.org/doi/abs/10.1021/bk-2008-0993.ch039
10. DNA protection- MDA (oxidative stress related) DNA adducts in heavy smokers
Conducted by: University of Illinois College of Medicine
Published in: Brief report published in American Association for Cancer Research Annual Meeting: Proceedings; 2007
Description: 203 people, double-blind, placebo-controlled, one month trial
Results: TNJ reduced the amount of MDA caused DNA damage by 53%
Link: http://www.abstractsonline.com/viewer/viewAbstract.asp?CKey=%7bC9ADCEF2-C9A3-4D02-922B-1982DDD964AF%7d&MKey=%7bE3F4019C-0A43-4514-8F66-B86DC90CD935%7d&AKey=%7b728BCE9C-121B-46B9-A8EE-DC51FDFC6C15%7d&SKey=%7b2C920D5B-ABFF-48AE-87CD-2A02FF72788B%7d
11. Menopause
Conducted by: The University of Illinois College of Medicine
Published in: Journal of Alternative & Complimentary Medicine
Description: 8 post-menopausal women , placebo-controlled, three month pilot study
Results: TNJ increased improved mood and energy, attenuated hearing loss, and showed evidence of potential anti-osteoporosis effect
Link: http://www.liebertonline.com/doi/abs/10.1089%2Facm.2004.10.737
12. Cholesterol—non-smoker
Conducted by: Brigham Young University Hawaii
Published in: Brief report in Proceedings of The 237th American Chemical Society National Meeting; 2009
Description: 10 people, one month pilot study
Results: Already healthy cholesterol values remained within healthy normal range
TNJ has mild cholesterol lowering & HDL raising potential in non-smokers within the high end range of normal. This displays adaptogenic activity.
Link: http://oasys2.confex.com/acs/237nm/techprogram/P1214611.HTM
13. Osteoarthritis.
Conducted by: University of Illinois at Chicago, College of Medicine at Rockford
Description: Open label three-month intervention trial with 82 osteoarthritis patients. Dose was 3 oz. of TNJ per day
Results: Significant improvements in symptoms, such as pain and mobility, were observed, as well as improvements in quality of life factors. Clinical laboratory tests revealed a large margin of safety.
*Publication of the full paper is in process
14. Noni Leaf Serum (not Tahitian Noni® Bioactive Beverage™, but still a Tahitian Noni-based product)
Conducted by: Tahitian Noni Intl. R&D and BioScreen Testing Services, Inc.
Published in: Journal of Natural Medicines
Description: 25 people, skin protection study
Results: Noni leaf extracts in the serum protected the skin against ultraviolet ray (UV) induced redness & swelling (erythema) by approximately 350%.
Link:http://www.ncbi.nlm.nih.gov/pubmed/19283442?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=11
